Technology
Gene therapy relies on viral vectors for delivery:
Common viruses are engineered to deliver therapeutic genes to treat specific disease(s).
Our immune system targets any foreign entity…
The human immune system naturally generates antibodies to protect against any such foreign substances.
…these antibodies (NAbs) block delivery of gene therapy
These Vector Neutralizing Antibodies (known as NAbs) significantly hamper clinical progress.
NabGen’s therapeutics transiently and safely suppress all antibodies
Key differentiators of our NG antibody suppression platform
- Instantly blocks antibody activity
- More effective against Nabs: 100X – 1,000X
- Tunable duration of action: hours/days/weeks
- Universally compatible: vector and disease agnostic
- Delivered alone or as a formulation
- Redosable therapeutic model
- Optimized for clinical use and manufacturing